Also known as alopecia mucinosa What is follicular mucinosis? Follicular mucinosis is a rare disorder affecting hair-bearing skin, most commonly on the scalp, head and neck. The name of the condition comes from the accumulation of mucin jelly-like, semi-liquid material in the walls of hair follicles. Sometimes the mucin is visible to the naked eye, and the hair follicles are visibly prominent and seem to ooze a clear gelatinous material.

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Marie Lewars, D. E-mail: moc. The face, neck, and scalp are the most frequently affected sites, although lesions may occur on any site of the body. Histologically, the disorder is characterized by mucin deposition in the follicular epithelium. The condition is frequently divided into primary and secondary forms, with the latter form frequently associated with mycosis fungoides.

In this case report, we describe a child with follicular mucinosis of the back and trunk and discuss the clinical variants, histopathological pattern, and treatment options. The primary form occurs in children and young adults. In the absence of other disorders, it commonly shows localized lesions of the face, head and neck that have a tendency to resolve within two months to two years.

There are no clinical criteria to distinguish primary cases from cases associated with mycosis fungoides MF ; however, most patients with limited involvement tend to have a benign course. Despite this assumption, follow-up is essential. The child was otherwise healthy with a past medical history of atopic dermatitis and no previous surgeries. Her medications included: multi-vitamin, fish oil, and vitamin D. In her family history, her mother had seasonal allergies and father had hypertension and basal cell carcinoma.

At that time, no laboratory tests were ordered. Additional findings include lymphocytes that are sparse superficial perivascular and intraepidermal, a rare necrotic keratinocyte, and focal smudging of the dermoepidermal junction.

Associated follicular epithelial spongiosis is, for the most part, mild, though there is focal spongiosis that may be graded as moderate. Colloidal iron stains at multiple levels from both specimens demonstrate mucin, both within the infundibular epithelium and the perifollicular sheath.


Follicular Mucinosis

E-mail: moc. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Follicular mucinosis, also known as alopecia mucinosa, is a cutaneous mucinosis histologically characterized by accumulation of dermal type mucin in the pilosebaceous follicle and sebaceous glands. It presents in two forms, a primary or idiopathic form and a secondary form associated with various benign or malignant processes. Among the malignant processes, the main association is with mycosis fungoides.


Follicular mucinosis

Who to contact? The basis of follicular mucinosis is degenerative changes in the hair follicle and sebaceous glands with the destruction of their structure and the deposition of glucosaminoglycans mucin. Reticular erythematous mucinosis syn: REM-syndrome was first described by L. Lischka and D.


Mucinosis folicular


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