Caratteristiche strutturali e fisiche[ modifica modifica wikitesto ] Ritodrina si presenta come una polvere cristallina bianca o quasi bianca, inodore o praticamente inodore. Risulta invece praticamente insolubile in etere. La ritodrina fornisce una colorazione nera al test di Liebermann e verde al test di Mandelin. Alle dosi terapeutiche si possono tuttavia manifestare cronotropismo positivo e vasodilatazione periferica, oltre che effetti metabolici quali aumento della glicemia e degli acidi grassi liberi plasmatici e diminuzione della potassiemia. Le concentrazioni plasmatiche massime Cmax sono raggiunte entro minuti. Usi clinici[ modifica modifica wikitesto ] Il farmaco viene principalmente impiegato allo scopo di impedire il parto prematuro, in assenza di altre complicazioni.
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All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breastfeeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking ritodrine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using ritodrine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other medical problems The presence of other medical problems may affect the use of ritodrine. Make sure you tell your doctor if you have any other medical problems, especially: Diabetes or High blood pressure hypertension , uncontrolled, or Migraine headaches or history of —May make these conditions worse.
Heart or blood vessel disease or Overactive thyroid, uncontrolled—May cause serious side effects on the heart, including irregular heartbeat. Proper use of ritodrine Dosing The dose of ritodrine will be different for different patients. The following information includes only the average doses of ritodrine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form extended-release capsules : Adults: In the first twenty-four hours after the doctor stops your intravenous ritodrine, your dose may be as high as 40 milligrams mg every eight hours.
After that, the dose is usually 40 mg every eight to twelve hours. Your doctor may want you to take oral ritodrine up until it is time for you to deliver your baby or until your 37th week of pregnancy. For oral dosage form tablets : Adults: In the first twenty-four hours after the doctor stops your intravenous ritodrine, your dose may be as high as 10 milligrams mg every two hours.
After that, the dose is usually 10 to 20 mg every four to six hours. For injection dosage form: Adults: 50 to micrograms per minute, injected into a vein. Missed dose If you miss a dose of ritodrine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Do not double doses. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Precautions while using ritodrine Check with your doctor right away if your contractions begin again or your water breaks. Do not take other medicines unless they have been discussed with your doctor. This especially includes over-the-counter nonprescription medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems since they may increase the unwanted effects of ritodrine.
Ritodrine side effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common.